Daniel Côté, professeur agrégé
Pavillon d'Optique photonique - Local 2141
T. 418 656-2131 poste 412510
Champs d'intérêts
  • Neurophotonique
  • Biophotonique
  • Maladie du cerveau (sclérose en plaques, douleur chronique, maladie de Parkinson)


  • PHY-2004, GPH-2005 : Optique et optique instrumentale
  • GPH-2004 : Travaux pratique en optique photonique I
  • PHY-7093: Travaux pratique en biophotonique
  • BPH-7005 : Imagerie biomedicale
  • BPH-7006 : Optique Linéaire et Nonlinéaire des tissus


  1. V. Breton-Provencher, D. Côté, and A. Saghatelyan, “Activity of the Principal Cells of the Olfactory Bulb Promotes a Structural Dynamic on the Distal Dendrites of Immature Adult-Born Granule Cells via Activation of NMDA Receptors,” J Neurosci, vol. 34, no. 5, pp. 1748–1759, Jan. 2014.
  2. A. Gasecka, A. Daradich, H. Dehez, M. Piché, and D. Côté, “Resolution and contrast enhancement in coherent anti-Stokes Raman-scattering microscopy.,” Opt Lett, vol. 38, no. 21, pp. 4510–4513, Nov. 2013.
  3. S. Bégin, E. Bélanger, S. Laffray, B. Aubé, É. Chamma, J. Bélisle, S. Lacroix, Y. De Koninck, and D. Côté, “Local assessment of myelin health in a multiple sclerosis mouse model using a 2D Fourier transform approach,” Biomed Opt Express, vol. 4, no. 10, pp. 2003–2014, 2013.
  4. E. Bélanger, J. Crépeau, S. Laffray, R. Vallée, Y. De Koninck, and D. Côté, “Live animal myelin histomorphometry of the spinal cord with video-rate multimodal nonlinear microendoscopy,” J Biomed Opt, vol. 17, no. 2, pp. 021107–021107–7, 2012.
  5. E. Bélanger, F. P. Henry, R. Vallée, M. A. Randolph, I. E. Kochevar, J. M. Winograd, C. P. Lin, and D. Côté, “In vivo evaluation of demyelination and remyelination in a nerve crush injury model.,” Biomed Opt Express, vol. 2, no. 9, pp. 2698–2708, Sep. 2011.
  6. S. M. Choi, W. H. Kim, D. Côté, C.-W. Park, and H. Lee, “Blood cell assisted in vivo Particle Image Velocimetry using the confocal laser scanning microscope.,” Opt. Expr., vol. 19, no. 5, pp. 4357–4368, Feb. 2011.
  7. J. Imitola, D. Côté, S. Rasmussen, X. S. Xie, Y. Liu, T. Chitnis, R. L. Sidman, C. P. Lin, and S. J. Khoury, “Multimodal coherent anti-Stokes Raman scattering microscopy reveals microglia-associated myelin and axonal dysfunction in multiple sclerosis-like lesions in mice.,” J Biomed Opt, vol. 16, no. 2, p. 021109, Feb. 2011.
  8. O. D. Therrien, B. Aubé, S. Pagès, P. D. Koninck, and D. Côté, “Wide-field multiphoton imaging of cellular dynamics in thick tissue by temporal focusing and patterned illumination.,” Biomed Opt Express, vol. 2, no. 3, pp. 696–704, 2011.
  9. S. Bégin, B. Burgoyne, V. Mercier, A. Villeneuve, R. Vallée, and D. Côté, “Coherent anti-Stokes Raman scattering hyperspectral tissue imaging with a wavelength-swept system.,” Biomed Opt Express, vol. 2, no. 5, pp. 1296–1306, 2011.
  10. S. Pagès, D. Côté, and P. De Koninck, “Optophysiological approach to resolve neuronal action potentials with high spatial and temporal resolution in cultured neurons.,” Front Cell Neurosci, vol. 5, p. 20, 2011.
  11. J. Fujisaki, J. Wu, A. L. Carlson, L. Silberstein, P. Putheti, R. Larocca, W. Gao, T. I. Saito, C. lo Celso, H. Tsuyuzaki, T. Sato, D. Côté, M. Sykes, T. B. Strom, D. T. Scadden, and C. P. Lin, “In vivo imaging of Treg cells providing immune privilege to the haematopoietic stem-cell niche.,” Nature, vol. 474, no. 7350, pp. 216–219, 2011.
  12. S. Laffray, S. Pagès, H. Dufour, P. De Koninck, Y. De Koninck, and D. Côté, “Adaptive Movement Compensation for In Vivo Imaging of Fast Cellular Dynamics within a Moving Tissue.,” PLoS ONE, vol. 6, no. 5, p. e19928, 2011.
  13. Chunqiang Li, C. Pitsillides, J. M. Runnels, D. Côté, and C. P. Lin, “Multiphoton Microscopy of Live Tissues With Ultraviolet Autofluorescence,” Ieee J Sel Top Quant, vol. 16, no. 3, pp. 516–523, May 2010.
  14. C. Li, R. K. Pastila, C. Pitsillides, J. M. Runnels, M. Puoris'haag, D. Côté, and C. P. Lin, “Imaging leukocyte trafficking in vivo with two-photon-excited endogenous tryptophan fluorescence,” Opt. Expr., vol. 18, no. 2, pp. 988–999, 2010.
  15. S. Bégin, E. Bélanger, S. Laffray, R. Vallée, and D. Côté, “In vivo optical monitoring of tissue pathologies and diseases with vibrational contrast.,” J Biophotonics, vol. 2, no. 11, pp. 632–642, Nov. 2009.
  16. F. P. Henry, D. Côté, M. A. Randolph, E. A. Z. Rust, R. W. Redmond, I. E. Kochevar, C. P. Lin, and J. M. Winograd, “Real-time in vivo assessment of the nerve microenvironment with coherent anti-Stokes Raman scattering microscopy.,” Plast. Reconstr. Surg., vol. 123, no. 2, pp. 123S–30S, Feb. 2009.
  17. C. lo Celso, H. E. Fleming, J. W. Wu, C. X. Zhao, S. Miake-Lye, J. Fujisaki, D. Côté, D. W. Rowe, C. P. Lin, and D. T. Scadden, “Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche.,” Nature, vol. 457, no. 7225, pp. 92–96, Jan. 2009.
  18. E. Bélanger, S. Bégin, S. Laffray, Y. De Koninck, R. Vallée, and D. Côté, “Quantitative myelin imaging with coherent anti-Stokes Raman scattering microscopy: alleviating the excitation polarization dependence with circularly polarized laser beams,” Opt. Expr., vol. 17, no. 21, pp. 18419–18432, 2009.
  19. M. F. G. Wood, D. Côté, and I. A. Vitkin, “Combined optical intensity and polarization methodology for analyte concentration determination in simulated optically clear and turbid biological media.,” J Biomed Opt, vol. 13, no. 4, p. 044037, Jun. 2008.
  20. I. Veilleux, J. Spencer, D. Biss, D. Côté, and C. P. Lin, “In Vivo Cell Tracking With Video Rate Multimodality Laser Scanning Microscopy,” IEEE J. Quant. Elect., vol. 14, no. 1, pp. 10–18, Jan. 2008.
  21. P. Kim, M. Puoris'haag, D. Côté, C. P. Lin, and S. H. Yun, “In vivo confocal and multiphoton microendoscopy.,” J Biomed Opt, vol. 13, no. 1, p. 010501, 2008.
  22. E. Bélanger, M. Bernier, D. Faucher, D. Côté, and R. Vallée, “High-Power and Widely Tunable All-Fiber Raman Laser,” Lightwave Technology, Journal of, vol. 26, no. 9, pp. 1696–1701, 2008.
  23. E. Bélanger, M. Bernier, J. P. Bérubé, B. Déry, S. Gagnon, D. Côté, and R. Vallée, “Two different mechanical tuning devices of fiber Bragg gratings,” Proc. SPIE Int. Soc. Opt. Eng., vol. 6796, no. 1, pp. 67962Q–11, Jun. 2007.
  24. E. Bélanger, M. Bernier, D. Côté, and R. Vallée, “All-fiber Raman laser tuned over 60nm,” Proc. SPIE Int. Soc. Opt. Eng., vol. 6796, no. 1, pp. 67960V–5, Jun. 2007.
  25. Y. Alsayed, H. Ngo, J. Runnels, X. Leleu, U. K. Singha, C. M. Pitsillides, J. A. Spencer, T. Kimlinger, J. M. Ghobrial, X. Jia, G. Lu, M. Timm, A. Kumar, D. Côté, I. Veilleux, K. E. Hedin, G. D. Roodman, T. E. WitZig, A. L. Kung, T. Hideshima, K. C. Anderson, C. P. Lin, and I. M. Ghobrial, “Mechanisms of regulation of CXCR4/SDF-1 (CXCL12)-dependent migration and homing in multiple myeloma.,” Blood, vol. 109, no. 7, pp. 2708–2717, Apr. 2007.
  26. M. Allard, D. Côté, L. Davidson, J. Dazai, and R. M. Henkelman, “Combined magnetic resonance and bioluminescence imaging of live mice.,” J Biomed Opt, vol. 12, no. 3, p. 034018, Apr. 2007.
  27. D. P. Biss, D. Sumorok, S. A. Burns, R. H. Webb, Y. Zhou, T. G. Bifano, D. Côté, I. Veilleux, P. Zamiri, and C. P. Lin, “In vivo fluorescent imaging of the mouse retina using adaptive optics,” Opt Lett, vol. 32, no. 6, pp. 659–661, Jan. 2007.
  28. C. Alt, I. Veilleux, H. Lee, C. M. Pitsillides, D. Côté, and C. P. Lin, “Retinal flow cytometer,” Opt Lett, vol. 32, no. 23, pp. 3450–3452, 2007.
  29. R. Chakraverty, D. Côté, J. Buchli, P. Cotter, R. Hsu, G. Zhao, T. Sachs, C. M. Pitsillides, R. Bronson, T. Means, C. P. Lin, and M. Sykes, “An inflammatory checkpoint regulates recruitment of graft-versus-host reactive T cells to peripheral tissues.,” J Exp Med, vol. 203, no. 8, pp. 2021–2031, Aug. 2006.
  30. C. L. Evans, E. O. Potma, M. Puoris'haag, D. Côté, C. P. Lin, and X. S. Xie, “Chemical imaging of tissue in vivo with video-rate coherent anti-Stokes Raman scattering microscopy.,” Proceedings of the National Academy of Sciences of the United States of America, vol. 102, no. 46, pp. 16807–16812, Nov. 2005.
  31. D. A. Sipkins, X. Wei, J. W. Wu, J. M. Runnels, D. Côté, T. K. Means, A. D. Luster, D. T. Scadden, and C. P. Lin, “In vivo imaging of specialized bone marrow endothelial microdomains for tumour engraftment.,” Nature, vol. 435, no. 7044, pp. 969–973, Jun. 2005.
  32. D. Côté and A. Vitkin, “Robust concentration determination of optically active molecules in turbid media with validated three-dimensional polarization sensitive Monte Carlo calculations,” Opt. Expr., vol. 13, no. 1, pp. 148–163, 2005.
  33. C. A. Rendon, D. Côté, L. Vesselov, and L. Lilge, “Characterization of the Modeled Fluence Distribution of Real Cylindrical Diffusers in the Intraluminal and Interstitial Settings,” presented at the Therapeutic Laser Applications and Laser-Tissue Interactions II, 2005, p. TuA2.
  34. D. Côté and I. A. Vitkin, “Balanced detection for low-noise precision polarimetric measurements of optically active, multiply scattering tissue phantoms,” J Biomed Opt, vol. 9, no. 1, pp. 213–220, Jan. 2004.
  35. D. Côté, J. Sipe, and H. van Driel, “Simple Method for Calculating the Propagation of THz Radiation In Experimental Geometries,” Journ. Opt. Soc. Am. B, 2003.
  36. D. Côté, N. Laman, and H. van Driel, “Rectification and shift currents in GaAs,” Appl Phys Lett, vol. 80, no. 6, p. 905, 2002.
  37. D. Côté, J. Fraser, M. DeCamp, P. Bucksbaum, and H. van Driel, “THz radiation from coherently-controlled photocurrents in GaAs,” Appl Phys Lett, vol. 75, no. 25, p. 3959, 1999.
  38. D. Côté and H. van Driel, “Period doubling of a femtosecond Ti:sapphire laser by total mode locking,” Opt Lett, vol. 23, p. 715, 1998.


Formation et expériences professionnelles

  • Ph.D.- Physics (University of Toronto, 2003)
  • M.Sc.- Physics (University of Toronto, 1996)
  • Baccalauréat ès sciences (Université Laval, 1995)
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